Grants & Publications

COR Selected Publications

1. Kim DW, Kim KO, Shin MJ, Ha JH, Seo SW, Yang J, Lee FY: siRNA-Based Targeting of Antiapoptotic Genes Can Reverse Chemoresistance in P-glycoprotein Expressing Chondrosarcoma Cells. J Molecular Cancer. In press.

2. Ahmad CS, Vorys GC, Covey A, Levine WN, Gardner TR, Bigliani LU: Rotator Cuff Repair Fluid Extravasation Characteristics are Influenced by Repair Technique. Journal of Shoulder and Elbow Surgery. In press.

3. Moffat KL, Doty S, Spalatzi J, Levine WN, Lu H: Novel Nanofiber-based Scaffold for Rotator Cuff Repair and Augmentation. Tissue Engineering. In press.

4. Gonzalez-Lomas G, Kippe MA, Brown GA, Ding A, Gardner TR, Levine WN, Ahmad CS: In-Situ Trans-tendon Repair Outperforms Tear Completion and Repair for Partial Articular-sided Supraspinatus Tendon Tears. J Shoulder Elbow Surg. In press.

5. Chambers A, Prince D, Greisberg J: Apoptosis and Nitric Oxide in Chondrocyte Following Trauma. J of Trauma. In press.

6. Tang P, Gauvin J, Muriuki M, Pfaeffle JH, Imbriglia JE, Goitz RJ: Comparison of the “Contact Mechanics” of the Intact and Proximal Row Carpectomy Wrist: J Hand Surg, 34A:660-670, 2009.

7. Sanjeev Suratwala, Samuel K. Cho, Jonathan Van Rattle, Sang H Park, Sung W Seo, Seong-Sil chang, Thomas R. Gardner, Lee, FY: Enhancement of periprosthetic bone quality with topical hydroxyapatite-bisphosphonate composite: An Experimental Study. The Journal of Bone and Joint Surgery, 90A(10):2189-2195, 2008.

8. Tuan RS, Lee FY, Konttinen YT, Wilkinson JM, Smith RL: What are the local and systemic biologic reactions and mediators to wear debris, and what host factors determine or modulate the biologic response to wear particles? Journal of American Academy of Orthopaedic Surgeons, 16(S):42-48, 2008.

9. Ahmad CS, Gardner T, Bell J, Levine WN: Biomechanical Performance of Rotator Cuff Repairs with Humeral Rotation: A New Rotator Cuff Repair Failure Model. Am J Sports Med, Apr 9, 2008 [Epub ahead of print].

10. Gonzalez-Lomas G, Kippe MA, Brown GA, Ding A, Gardner TR, Levine WN, Ahmad CS: In-Situ Trans-Tendon Repair Outperforms Tear Completion and Repair for Partial Articular-Sided Supraspinatus Tendon Tears. Journal of Shoulder and Elbow Surgery, 17: 722-728, 2008.

11. Kowlosky MS, Dellenbaugh SG, Erlichman DB, Gardner TR, Levine, WN, Ahmad CS: Evaluation of Suture Abrasion Against Rotator Cuff Tendon and Proximal Humerus Bone. Arthroscopy, 24:329-334, 2008.

12. Ahmad CS, Kleweno C, Jacir A, Bell JE, Gardner TR, Levine WN, Bigliani LU: Biomechanical Performance of Rotator Cuff Repairs with Humeral Rotation: A New Rotator Cuff Repair Failure Model. American Journal of Sports Medicine, 36:888-92, 2008.

13. Celil Aydemir AB, Lee S, Won Kim D, Gardner TR, Prince D, Mok Ahn J, Lee FY: Calcineurin/NFATc axis mediated fluid shear stress-induced COX-2 expression in human mesenchymal cells. The Annals of New York Academy of Science,1117:138-42; Nov, 2007.

14. Seo SW, Aydemir A, Minematsu H, Lee FY: ERK Signaling Regulates M-CSF Expression Induced by Titanium Nanoparticles in MC3T3-E1 Murine Calvarial Pre-Osteoblastic Cells. The Annals of New York Academy of Science, 1117:151-8; Nov, 2007.

15. Minematsu H, Seo S, Aydemir A, Lee FY: Calcomeirom/NFATC1 Axis Regulates UHMWPE Wear Particle-Induced Cytokine Expression in Macrophages: The Annals of New York Academy of Science, 1117:143-50; Nov, 2007.

16. Park MC, Jun BJ, Park CJ, Ahmad CS, Elattrache NS, Lee TQ: The Biomechanical Effects of Dynamic External Rotation on Rotator Cuff Repair Compared to Testing With the Humerus Fixed. American Journal of Sports Medicine, 35:1931-9, 2007.

17. Ahmad CS, DiSipio K, Gardner TR, Levine WN, Bigliani LU: Factors Affecting Dropped Biceps Deformity After Tenotomy of the Long Head of the Biceps Tendon. Arthroscopy, 23:537-41, 2007.

18. Ahmad CS, Wing DE, Gardner T, Levine WN, Bigliani LU: Biomechanical evaluation of subscapularis repair used during shoulder arthroplasty. J Shoulder and Elbow Surg,16 (3 Suppl):S59-6.4; May-June, 2007.

19. Kim DW, Seo SW, Cho S, Chang SS, Lee HW, Lee SE, Block JA, Hei TK, Lee FY: Targeting of cell survival genes using small interfering RNAs (siRNAs) enhances radiosensitivity of Grade II chondrosarcoma cells. Journal of Orthopaedic Research, 25(6):820-8; March 7, 2007.

20. Park MC, Elattrache, NS, Tibone JE, Ahmad CS, Jun BJ, Lee TQ: Part I: Footprint Contact Characteristics for a “Transosseous-Equivalent” Rotator Cuff Repair Technique Compared to a Double-Row Technique. Journal of Shoulder and Elbow Surgery, 16:461-8, 2007.

21. Spalazzi JP, Doty SB, Moffat KL, Levine WN, Lu HH: Development of controlled matrix heterogeneity on a triphasic scaffold for orthopaedic interface tissue engineering: Tissue Engineering, 12: 3497-3508, 2006.

22. Lee FY, Sinicropi S, Vitale MG, Lee FS, Roye DP, Choi IH: Treatment of congenital pseudarthrosis of tibia with recombinant human bone morphogenetic protein-7: A prospective study. Journal of Bone and Joint Surgery, 88(3):627-33; Mar,2006.

23. Kim YS, Bigliani LU, Fujisawa M, Murakami K, Chang SS, Lee HJ, Lee FY, Blaine TA: Stromal cell-derived factor 1 (SDF-1, CXCL12) is increased in subacromial bursitis and downregulated by steroid and nonsteroidal anti-inflammatory agents. Journal of Orthopaedic Research, 24: 1756-64; June, 2006.

24. Ahmad CS, Wing D, Gardner TR, Levine WN, Bigliani LU: Biomechanical Evaluation of Subscapularis Repairs Used During Total Shoulder Replacement. Journal of Shoulder and Elbow Surgery, 16:s59-64, 2006.

25. Kim DW, Lee HJ, Karmin J, Lee SE, Chang SS, Tolchin B, Lin S, Cho SK, Kwon A, Ahn JM, and Lee FY: Mechanical Loading Differentially Regulates Membrane-Bound and Soluble RANKL Availability in MC3T3-E1 Cells. Annals of New York Academy of Science, Vol 1068, pp568-572, April, 2006.

26. Park M, Cadet E, Levine, WN, Bigliani LU, Ahmad CS: Comparison of Rotator Cuff Tendon Pressure Against the Tuberosity in Suture Anchor and Transosseous Suture Rotator Cuff Repairs. American Journal of Sports Medicine, 33:1154-9, 2005.

27. Lee FY, Kim DW, Karmin JA, Hong D, Chang SS, Fujisawa M, Takayanagi H, Bigliani LU, Blaine TA, Lee HJ: mu -calpain regulates RANKL-supported osteoclastogenesis via NF-kappa B activation in raw 264.7 cells. Journal of Biological Chemistry, 280(33):29929-36; June 13, 2005.

28. Yu J, Chang SS, Suratwala S, Chung W, Abdelmessieh P, Lee HJ, Yang J, Lee FY: Zoledronate induces apoptosis in stromal cells of unicameral bone cyst. Journal of Orthopaedic Research, 23(5):1004-122005; May 24, 2005.

29. Blaine TA, Kim YS, Voloshin I, Chen D, Murakami K, Chang SS, Winchester R, Lee FY, O'Keefe RJ, Bigliani LU: The molecular pathophysiology of subacromial bursitis in rotator cuff disease. J Shoulder Elbow Surg, 14(1 Suppl S):84S-89S; Jan-Feb, 2005.

30. Liao T, Yurgelun M, Chang SS, Murakami K, Zhang HZ, Parisien MV, Blaine TA, Kim W, Winchester RJ, Lee FY: Recruitment of osteoclast precursors by stromal cell derived factor-1 in giant cell tumor of bone. Journal of Orthopaedic Research, 23(1):203-9; Jan, 2005.

31. Yoon AJ, Parisien M, Feldman F, Lee FY: Extranodal Rosai-Dorfman disease of bone, subcutaneous tissue and paranasal sinus mucosa: Case report and review of the literature. Skeletal Radiology, 34(10):653-7; Oct, 2005.

32. Delloye C, Suratwala S, Valentin-Opran A, Cornu O, Lee FY: Treatment of Allograft Nonunions with Recombinant Human Bone Morphogenetic Proteins (rhBMP): Early Clinical Results. ACTA Orthopaedica Belgica, 70:591-597, 2004.

33. Chang SS, Suratwala S, Jung KM, Doppelt J, Zhang HJ, Blaine TA, Kim TW, Winchester RJ, Lee FY: Bisphosphonate may reduce recurrence in GCT by inducing apoptosis. Clinical Orthopaedics and Related Research, September, 426:103-109, 2004.

34. Lee FY, Hornicek FJ, Dick HM, Mankin HJ: Synovial chondromatosis of the foot. Clinical Orthopaedic and Related Research, April, 423:186-190, 2004.

35. Ahmad CS, Groh M, Arnouk J, Gardner TR, Levine WN: Mechanical properties of soft tissue femoral fixation devices for ACL reconstruction. Am J Sports Med, 32: 1-10, 2004.

36. Vitale MG, Choe JC, Hwang MW, Bauer RM, Hyman JE, Lee FY, Roye DP: Postoperative Use of Ketorolac Tromethamine in Children Undergoing Scoliosis Surgery. The Spine Journal, 3:55-62; 2003.

37. Lee FY, Storer SK, Hazan EJ, Gebhardt MC, Mankin HJ: Repair of bone allograft fracture using bone morphogenetic protein-2 in an animal experimental model. Clinical Orthopaedics and Related Research, April, 397:119-126, 2002.

38. Lee FY, Zawadsky M, Parisien M, Ho M, Murty VV, Jayaraman T, Dick HM: A novel translocation (9;12)(q22;q24) in secondary chondrosarcoma arising from hereditary multiple exostosis. Cancer Genetics and Cytogenetics, 132(1)68-70; 2002.

39. Lee FY, Hazan EJ, Gebhardt MC, Mankin HJ. An experimental model for allograft fracture repair. Journal of Orthopaedic Research, 18:303-306, 2000.

40. Ramappa AJ, Lee FY, Tang P, Carlson JR, Gebhardt MC, Mankin HJ: Chondroblastoma of bone. Journal of Bone and Joint Surgery, 82A:1140-1145, 2000.

41. Lee FY, Mankin HJ, Gebhardt MC, Springfield D, Fondren G, Jennings LC, Rosenberg A. Outcome analysis of chondrosarcoma. Journal of Bone and Joint Surgery, (Am) 81A: 326-338, 1999.

42. Lee FY, Rho JY, Harten R, Parsons JR, Behrens FF. Micromechanical Properties of Primary Spongiosa and Epiphyseal Trabecular Bone. Journal of Pediatric Orthopaedics, 18: 582-585, 1998.

43. Lee FY, Behrens FF, DeFouw DO, and Einhorn TA: Programmed Removal of Chondrocytes During Enchondral Fracture Healing. Journal of Orthopaedic Research, 16(1), 144-149, 1998.

44. Lee FY, Gebhardt MC, Keel SB, Rosenthal DI. Orthopaedic-Pathology-Radiology Conference. A discrete soft tissue mass in the distal thigh of 29-year–old male. Clinical Orthopaedics and Related Research, 357: 247-250, 1998.

45. Benevenia J, Lee FY, Buechel FF, Parsons JR: Aggressive Granulomatous Lesion following Total Knee Replacement Arthroplasty. Journal of Biomedical Materials Research Applied Biomaterials, 43(4):473-477, 1998.

46. Seong SC, Matsumura T, Lee FY, Whelan MC, Li XQ and Trippel SB: Insulin-like growth factor I regulation of Swarm rat chondrosarcoma chondrocytes in culture. Experimental Cell Research 211:238-244, 1994.

47. Kim YM, Lee SH, Lee FY, Koo KH and Cho KH: Morphologic and biomechanical study of avascular necrosis of the femoral head. Orthopaedics 14:1111-1116, 1991.